A New Frontier in Peyronie’s Disease Treatment
At Menspro Health™, we’re excited to launch CurveX™—a cutting-edge, non-surgical treatment protocol for Peyronie’s Disease (PD). With an estimated 9% of men affected by this condition, the need for effective treatments is clear. We’re proud to offer one of the most comprehensive approaches in the U.S., combining CurveX™ with proven options like Xiaflex®, Acoustic Wave Therapy with Platelet-Rich Plasma (PRP), Vacuum Erection Devices (VEDs), and Verapamil injections for acute cases.
What Is Peyronie’s Disease?
Peyronie’s Disease occurs when fibrous scar tissue, or plaque, forms inside the penis—often due to injury or trauma—causing curved, sometimes painful erections. This can affect both function and confidence, with severity ranging from mild to significant curvature, and in some cases, indentations or “hourglass” deformities from scar contraction. For men with mild to moderate PD and intact erectile function, conservative options like Xiaflex can help, but effectiveness tends to decrease as curvature worsens. For severe cases, surgery remains the most reliable approach.
A Full Spectrum of Options
At Menspro Health™, we personalize your care with a range of advanced treatments:
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- Xiaflex®: The only FDA-approved injectable for PD, suitable for mild to moderate cases with intact erectile function.
- CurveX™: Our pioneering HA-based option, designed as an alternative for similar cases, with no known fracture risk and added aesthetic benefits.
- Acoustic Wave Therapy with PRP: A non-invasive therapy combining low-intensity shockwaves and platelet-rich plasma to promote tissue health, reduce pain, and support penile rehabilitation. In our clinics, we’ve seen encouraging results with this approach, particularly for pain relief and modest curvature improvement in early PD cases.
- Vacuum Erection Devices (VEDs): A complementary tool that uses suction to improve blood flow, often paired with acoustic wave therapy and PRP for enhanced outcomes.
- Verapamil Injections: An option for very acute PD cases, delivering a calcium channel blocker to potentially reduce plaque formation and inflammation early on.
No other clinic in the country combines this array of PD treatments, making Menspro Health™ a leader in non-surgical urological care.
Potential Benefits of CurveX™
- Targets plaque with precision intralesional injections
- May reduce curvature and improve function
- Fills in defects like divots or “hourglass” shapes for better aesthetics
- May stabilize erections by addressing scar-related deformities
- Minimally invasive with little to no downtime
- An option for men seeking conservative treatment in acute or chronic PD phases
- No associated penile fracture risk (unlike Xiaflex)
Additional Note: Acoustic Wave Therapy and/or PRP may help reduce pain and improve curvature, especially in early PD, based on clinical studies and our own experience, though results vary. All treatments require a consultation to assess suitability, as outcomes depend on individual factors and further research is ongoing.
Articles & Independent Studies:
Intraplaque injections of hyaluronic acid for the treatment of stable-phase Peyronie’s disease: a retrospective single-center experience
Current Evidence on the Use of Hyaluronic Acid as Nonsurgical Option for the Treatment of Peyronie’s Disease: A Contemporary Review
MDPI and ACS Style
Capece, M.; Celentano, G.; La Rocca, R. Current Evidence on the Use of Hyaluronic Acid as Nonsurgical Option for the Treatment of Peyronie’s Disease: A Contemporary Review. Uro 2023, 3, 160-167. https://doi.org/10.3390/uro3020017
AMA Style
Capece M, Celentano G, La Rocca R. Current Evidence on the Use of Hyaluronic Acid as Nonsurgical Option for the Treatment of Peyronie’s Disease: A Contemporary Review. Uro. 2023; 3(2):160-167. https://doi.org/10.3390/uro3020017
Chicago/Turabian Style
Capece, Marco, Giuseppe Celentano, and Roberto La Rocca. 2023. “Current Evidence on the Use of Hyaluronic Acid as Nonsurgical Option for the Treatment of Peyronie’s Disease: A Contemporary Review” Uro 3, no. 2: 160-167. https://doi.org/10.3390/uro3020017
APA Style
Capece, M., Celentano, G., & La Rocca, R. (2023). Current Evidence on the Use of Hyaluronic Acid as Nonsurgical Option for the Treatment of Peyronie’s Disease: A Contemporary Review. Uro, 3(2), 160-167. https://doi.org/10.3390/uro3020017
EFFICACY AND SAFETY OF INTRALESIONAL INJECTION OF HYALURONIC ACID (HA) FOR THE TREATMENT OF CHRONIC PHASE PEYRONIE’S DISEASE (PD): PRELIMINARY RESULTS FROM A PILOT STUDY
Why It Matters: Meeting an Unmet Need
For the 9% of men with PD, treatment options depend on severity. While surgery is the gold standard for severe curvature or significant erectile dysfunction, many prefer less invasive approaches for milder cases. CurveX™, alongside our expanded offerings, provides promising alternatives, with early experiences in our clinics showing encouragement. We’re dedicated to providing choices for men who want to explore conservative options first—as long as they understand surgery may ultimately be the most effective for severe PD.
Our Honest Answer: Your Path Forward
At Menspro Health™, we believe in straight talk and real results. When you come in, our expert medical team will evaluate your condition with care and give you an honest, no-nonsense answer about your best options—whether that’s CurveX™, Xiaflex, acoustic wave therapy with PRP, VEDs, verapamil, or surgery. Together, we’ll weigh the pros and cons, discuss the risks, benefits, and potential outcomes of all your options, and answer your questions to empower you to make an informed decision that’s right for you. No hype, just clarity—because your health deserves nothing less

Greater Nashville | Midtown
(615) 208-9090
info@tennesseemensclinic.com
210 23rd Ave N #201
Nashville, TN 37203
Mon – Fri: 9am – 5pm
(Closed Saturday and Sunday)
Tennessee Men's Clinic
Greater Nashville | Franklin
(615) 208-9090
info@tennesseemensclinic.com
2001 Mallory Ln STE 302
Franklin, TN 37067
Mon – Fri: 9am – 5pm
(Closed Saturday and Sunday)

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